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Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery
Impressive progress in genome sequencing, protein expression and high-throughput crystallography and NMR has radically transformed the opportunities to use protein three-dimensional structures to accelerate drug discovery, but the quantity and complexity of the data have ensured a central place for...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1609333/ https://ncbi.nlm.nih.gov/pubmed/16524830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1800 |
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