Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

Impressive progress in genome sequencing, protein expression and high-throughput crystallography and NMR has radically transformed the opportunities to use protein three-dimensional structures to accelerate drug discovery, but the quantity and complexity of the data have ensured a central place for...

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Autors principals: Blundell, Tom L, Sibanda, Bancinyane L, Montalvão, Rinaldo Wander, Brewerton, Suzanne, Chelliah, Vijayalakshmi, Worth, Catherine L, Harmer, Nicholas J, Davies, Owen, Burke, David
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609333/
https://ncbi.nlm.nih.gov/pubmed/16524830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1800
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