Morphine Modulation of Thrombospondin Levels in Astrocytes and Its Implications for Neurite Outgrowth and Synapse Formation

Opioid receptor signaling via EGF receptor (EGFR) transactivation and ERK/MAPK phosphorylation initiates diverse cellular responses that are cell type-dependent. In astrocytes, multiple μ opioid receptor-mediated mechanisms of ERK activation exist that are temporally distinctive and feature differen...

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Autores principales: Ikeda, Hiroko, Miyatake, Mayumi, Koshikawa, Noriaki, Ochiai, Kuniyasu, Yamada, Kiyoshi, Kiss, Alexi, Donlin, Maureen J., Panneton, W. Michael, Churchill, James D., Green, Michael, Siddiqui, Akbar M., Leinweber, Andrew L., Crews, Nicholas R., Ezerskiy, Lubov A., Rendell, Victoria R., Belcheva, Mariana M., Coscia, Carmine J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992274/
https://ncbi.nlm.nih.gov/pubmed/20889977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109827
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