Morphine Modulation of Thrombospondin Levels in Astrocytes and Its Implications for Neurite Outgrowth and Synapse Formation

Opioid receptor signaling via EGF receptor (EGFR) transactivation and ERK/MAPK phosphorylation initiates diverse cellular responses that are cell type-dependent. In astrocytes, multiple μ opioid receptor-mediated mechanisms of ERK activation exist that are temporally distinctive and feature differen...

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Detalhes bibliográficos
Main Authors: Ikeda, Hiroko, Miyatake, Mayumi, Koshikawa, Noriaki, Ochiai, Kuniyasu, Yamada, Kiyoshi, Kiss, Alexi, Donlin, Maureen J., Panneton, W. Michael, Churchill, James D., Green, Michael, Siddiqui, Akbar M., Leinweber, Andrew L., Crews, Nicholas R., Ezerskiy, Lubov A., Rendell, Victoria R., Belcheva, Mariana M., Coscia, Carmine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992274/
https://ncbi.nlm.nih.gov/pubmed/20889977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109827
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