Basis for MAP4 Dephosphorylation-related Microtubule Network Densification in Pressure Overload Cardiac Hypertrophy

Increased activity of Ser/Thr protein phosphatases types 1 (PP1) and 2A (PP2A) during maladaptive cardiac hypertrophy contributes to cardiac dysfunction and eventual failure, partly through effects on calcium metabolism. A second maladaptive feature of pressure overload cardiac hypertrophy that inst...

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Main Authors: Cheng, Guangmao, Takahashi, Masaru, Shunmugavel, Anandakumar, Wallenborn, J. Grace, DePaoli-Roach, Anna A., Gergs, Ulrich, Neumann, Joachim, Kuppuswamy, Dhandapani, Menick, Donald R., Cooper, George
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992246/
https://ncbi.nlm.nih.gov/pubmed/20889984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148650
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