Site-specific Microtubule-associated Protein 4 Dephosphorylation Causes Microtubule Network Densification in Pressure Overload Cardiac Hypertrophy

In severe pressure overload-induced cardiac hypertrophy, a dense, stabilized microtubule network forms that interferes with cardiocyte contraction and microtubule-based transport. This is associated with persistent transcriptional up-regulation of cardiac α- and β-tubulin and microtubule-stabilizing...

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Detalhes bibliográficos
Main Authors: Chinnakkannu, Panneerselvam, Samanna, Venkatesababa, Cheng, Guangmao, Ablonczy, Zsolt, Baicu, Catalin F., Bethard, Jennifer R., Menick, Donald R., Kuppuswamy, Dhandapani, Cooper, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898445/
https://ncbi.nlm.nih.gov/pubmed/20436166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120709
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