Heat Shock Protein 90 as a Drug Target against Protozoan Infections: BIOCHEMICAL CHARACTERIZATION OF HSP90 FROM PLASMODIUM FALCIPARUM AND TRYPANOSOMA EVANSI AND EVALUATION OF ITS INHIBITOR AS A CANDIDATE DRUG

Using a pharmacological inhibitor of Hsp90 in cultured malarial parasite, we have previously implicated Plasmodium falciparum Hsp90 (PfHsp90) as a drug target against malaria. In this study, we have biochemically characterized PfHsp90 in terms of its ATPase activity and interaction with its inhibito...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Pallavi, Rani, Roy, Nainita, Nageshan, Rishi Kumar, Talukdar, Pinaki, Pavithra, Soundara Raghavan, Reddy, Raghunath, Venketesh, S., Kumar, Rajender, Gupta, Ashok Kumar, Singh, Raj Kumar, Yadav, Suresh Chandra, Tatu, Utpal
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992230/
https://ncbi.nlm.nih.gov/pubmed/20837488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155317
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki