Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism

PPAR-α, PPAR-β, and PPAR-γ, and RXR in conjunction with PGC-1α and SIRT1, activate oxidative metabolism genes determining insulin sensitivity. In utero, hypoxia is commonly observed in Intrauterine Growth Restriction (IUGR), and reduced insulin sensitivity is often observed in these infants as adult...

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Bibliografiske detaljer
Main Authors: Regnault, Timothy R. H., Zhao, Lin, Chiu, Jacky S. S., Gottheil, Stephanie K., Foran, Allison, Yee, Siu-Pok
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991640/
https://ncbi.nlm.nih.gov/pubmed/21113404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/129173
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