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Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in mice
We investigated the hypothesis that a prominent effect of chronic ethanol consumption is mitochondrial DNA (mtDNA) injury and compared this injury in IL-6 knockout (KO) and wild-type (WT) mice. Ethanol feeding for 4 weeks resulted in steatosis and oxidative mtDNA damage (8-OHdG) in both IL-6KO and W...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991528/ https://ncbi.nlm.nih.gov/pubmed/20931558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23909 |
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