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Therapeutic Potential of Interleukin 1 Inhibitors in the Treatment of Alcoholic Liver Disease

Alcoholic liver disease (ALD) is characterized by steatosis and upregulation of proinflammatory cytokines, including IL-1β. IL-1β, type I IL-1 receptor (IL-1R1), and IL-1 receptor antagonist (IL-1Ra) are all important regulators of the IL-1 signaling complex, which plays a role in inflammation. Furt...

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Detalhes bibliográficos
Main Authors: Mathews, Stephanie, Gao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786181/
https://ncbi.nlm.nih.gov/pubmed/23609413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26336
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