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Redox Regulation of Guanylate Cyclase and Protein Kinase G in Vascular Responses to Hypoxia
The production of cGMP by the soluble form of guanylate cyclase (sGC) in bovine pulmonary arteries (BPA) is controlled by cytosolic NADPH maintaining reduced thiol and heme sites on sGC needed for activation by NO, and the levels of Nox oxidase-derived superoxide and peroxide that influence pathways...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991487/ https://ncbi.nlm.nih.gov/pubmed/20831906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2010.08.024 |
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