ANTI-11[E]-PYROGLUTAMATE-MODIFIED AMYLOID β ANTIBODIES CROSS-REACT WITH OTHER PATHOLOGICAL Aβ SPECIES: RELEVANCE FOR IMMUNOTHERAPY

N-truncated/modified forms of amyloid beta (Aß) peptide are found in diffused and dense core plaques in Alzheimer's disease (AD) and Down's syndrome patients as well as animal models of AD, and represent highly desirable therapeutic targets. In the present study we have focused on Ntruncat...

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Hauptverfasser: Perez-Garmendia, Roxanna, Ibarra-Bracamontes, Vanessa, Vasilevko, Vitaly, Luna-Muñoz, Jose, Mena, Raul, Govezensky, Tzipe, Acero, Gonzalo, Manoutcharian, Karen, Cribbs, David H., Gevorkian, Goar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991418/
https://ncbi.nlm.nih.gov/pubmed/20864186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.08.020
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