Wordt geladen...
Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome
Methylated cytosines within CpG dinucleotides (mCpGs) along the DNA-binding domain of the TP53 tumor suppressor gene (~ exons 5–8) are the single most significant mutational target in human cancers. The human p53 knock-in (Hupki) mouse model was constructed using gene-targeting technology to create...
Bewaard in:
| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991417/ https://ncbi.nlm.nih.gov/pubmed/20945503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20683 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|