Mcl-1 is Essential for Germinal Center Formation and B cell Memory

Lymphocyte survival during immune responses is controlled by the relative expression of pro-and anti-apoptotic molecules, regulating the magnitude, quality and duration of the response. Here we investigate the consequences of deleting genes encoding the anti-apoptotic molecules Mcl1 and Bcl2l1 (Bcl-...

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Main Authors: Vikstrom, Ingela, Carotta, Sebastian, Lüthje, Katja, Peperzak, Victor, Jost, Philipp J., Glaser, Stefan, Busslinger, Meinrad, Bouillet, Philippe, Strasser, Andreas, Nutt, Stephen L., Tarlinton, David M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991396/
https://ncbi.nlm.nih.gov/pubmed/20929728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191793
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