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The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells

In the healthy artery, contractile vascular smooth muscle cells (VSMCs) have an elongated shape and are highly aligned but transition to a synthetic phenotype in culture, while additionally becoming well spread and randomly organized. Thus, controlling VSMC phenotype is a challenge in tissue enginee...

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Detalles Bibliográficos
Main Authors: Williams, Corin, Brown, Xin Q, Bartolak-Suki, Erzsebet, Ma, Hongwei, Chilkoti, Ashutosh, Wong, Joyce Y
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991379/
https://ncbi.nlm.nih.gov/pubmed/20858564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.08.105
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