Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis

BACKGROUND: Although recent studies indicate a crucial role for IL-17A and IL-22 producing T cells in the pathogenesis of psoriasis, limited information is available on their frequency and heterogeneity and their distribution in skin in situ. METHODOLOGY/PRINCIPAL FINDINGS: By spectral imaging analy...

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Bibliografiske detaljer
Main Authors: Res, Pieter C. M., Piskin, Gamze, de Boer, Onno J., van der Loos, Chris M., Teeling, Peter, Bos, Jan D., Teunissen, Marcel B. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991333/
https://ncbi.nlm.nih.gov/pubmed/21124836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014108
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