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The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis

Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17, the major effector cytokine in the pathogenesis of psoriatic disease, along with the rationale for targeting the...

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Bibliographic Details
Published in:Clin Rev Allergy Immunol
Main Authors: Blauvelt, Andrew, Chiricozzi, Andrea
Format: Artigo
Language:Inglês
Published: Springer US 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244934/
https://ncbi.nlm.nih.gov/pubmed/30109481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12016-018-8702-3
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