Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components

BACKGROUND: Quantitative traits often underlie risk for complex diseases. For example, weight and body mass index (BMI) underlie the human abdominal obesity-metabolic syndrome. Many attempts have been made to identify quantitative trait loci (QTL) over the past decade, including association studies....

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Main Authors: Mei, Hao, Chen, Wei, Dellinger, Andrew, He, Jiang, Wang, Meng, Yau, Canddy, Srinivasan, Sathanur R, Berenson, Gerald S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991276/
https://ncbi.nlm.nih.gov/pubmed/21062472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-100
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