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Power analysis of principal components regression in genetic association studies

Association analysis provides an opportunity to find genetic variants underlying complex traits. A principal components regression (PCR)-based approach was shown to outperform some competing approaches. However, a limitation of this method is that the principal components (PCs) selected from single...

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Detalhes bibliográficos
Main Authors: Shen, Yan-feng, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759878/
https://ncbi.nlm.nih.gov/pubmed/19816996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B0830866
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