An epidermal growth factor receptor variant III–targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

Conventional therapies for glioblastoma multiforme (GBM) fail to target tumor cells exclusively, such that their efficacyis ultimately limited by nonspecific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epiderm...

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Bibliografische gegevens
Hoofdauteurs: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Herndon, James E., Lally-Goss, Denise, McGehee-Norman, Sharon, Paolino, Alison, Reardon, David A., Friedman, Allan H., Friedman, Henry S., Bigner, Darell D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991139/
https://ncbi.nlm.nih.gov/pubmed/19825799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0124
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