Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: Case study

Glioblastoma multiforme remains refractory to conventional therapy, and novel therapeutic modalities are desperately needed. TP-38 is a recombinant chimeric protein containing a genetically engineered form of the cytotoxic Pseudomonas exotoxin fused to transforming growth factor (TGF)-α. TGF-α binds...

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Библиографические подробности
Главные авторы: Sampson, John H., Reardon, David A., Friedman, Allan H., Friedman, Henry S., Coleman, R. Edward, McLendon, Roger E., Pastan, Ira, Bigner, Darell D.
Формат: Artigo
Язык:Inglês
Опубликовано: Duke University Press 2005
Предметы:
Case Studies
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871629/
https://ncbi.nlm.nih.gov/pubmed/15701286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851703000589
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