Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors

The purpose of this study is to determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and intracerebral distribution of a recombinant toxin (TP-38) targeting the epidermal growth factor receptor in patients with recurrent malignant brain tumors using the intracerebral infusion te...

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Détails bibliographiques
Auteurs principaux: Sampson, John H., Akabani, Gamal, Archer, Gerald E., Berger, Mitchel S., Coleman, R. Edward, Friedman, Allan H., Friedman, Henry S., Greer, Kim, Herndon, James E., Kunwar, Sandeep, McLendon, Roger E., Paolino, Alison, Petry, Neil A., Provenzale, James M., Reardon, David A., Wong, Terence Z., Zalutsky, Michael R., Pastan, Ira, Bigner, Darell D.
Format: Artigo
Langue:Inglês
Publié: Duke University Press 2008
Sujets:
Clinical Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563054/
https://ncbi.nlm.nih.gov/pubmed/18403491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-012
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