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An epidermal growth factor receptor variant III–targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

Conventional therapies for glioblastoma multiforme (GBM) fail to target tumor cells exclusively, such that their efficacyis ultimately limited by nonspecific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epiderm...

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書誌詳細
主要な著者: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Herndon, James E., Lally-Goss, Denise, McGehee-Norman, Sharon, Paolino, Alison, Reardon, David A., Friedman, Allan H., Friedman, Henry S., Bigner, Darell D.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991139/
https://ncbi.nlm.nih.gov/pubmed/19825799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0124
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