An epidermal growth factor receptor variant III–targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

Conventional therapies for glioblastoma multiforme (GBM) fail to target tumor cells exclusively, such that their efficacyis ultimately limited by nonspecific toxicity. Immunologic targeting of tumor-specific gene mutations, however, may allow more precise eradication of neoplastic cells. The epiderm...

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Autors principals: Sampson, John H., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., Herndon, James E., Lally-Goss, Denise, McGehee-Norman, Sharon, Paolino, Alison, Reardon, David A., Friedman, Allan H., Friedman, Henry S., Bigner, Darell D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991139/
https://ncbi.nlm.nih.gov/pubmed/19825799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0124
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