Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers

BACKGROUND: Colorectal, endometrial and upper urinary tract tumours are characteristic for Lynch syndrome (hereditary non-polyposis colon carcinoma, HNPCC). The aim of the present study was to establish whether carriers of mutations in mismatch repair genes MLH1, MSH2 or MSH6 are at increased risk o...

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Detalhes bibliográficos
Main Authors: van der Post, R S, Kiemeney, L A, Ligtenberg, M J L, Witjes, J A, Hulsbergen-van de Kaa, C A, Bodmer, D, Schaap, L, Kets, C M, van Krieken, J H J M, Hoogerbrugge, N
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991077/
https://ncbi.nlm.nih.gov/pubmed/20591884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2010.076992
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