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Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers
BACKGROUND: Germline mutations in MSH6 account for 10%–20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain. METHODS: We identified 113 families of MSH6 muta...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815724/ https://ncbi.nlm.nih.gov/pubmed/20028993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp473 |
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