Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression

INTRODUCTION: Th17 cells have been implicated in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to systematically analyse the phenotype, cytokine profile and frequency of interleukin-17 (IL-17) producing CD4-positive T cells in mononuclear cells isolated from peripheral blo...

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Detalhes bibliográficos
Main Authors: Church, Leigh D, Filer, Andrew D, Hidalgo, Esther, Howlett, Katherine A, Thomas, Andrew MC, Rapecki, Stephen, Scheel-Toellner, Dagmar, Buckley, Christopher D, Raza, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991017/
https://ncbi.nlm.nih.gov/pubmed/20929536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3152
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