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Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance

A cross-regulation between type I IFN and TNFα has been proposed recently, where both cytokines are hypothesized to counteract each other. According to this model, different autoimmune diseases can be viewed as disequilibrium between both cytokines. As this model may have important clinical implicat...

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Detalhes bibliográficos
Main Authors: Cantaert, Tineke, Baeten, Dominique, Tak, Paul P, van Baarsen, Lisa GM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991015/
https://ncbi.nlm.nih.gov/pubmed/21062511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3150
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