Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance

A cross-regulation between type I IFN and TNFα has been proposed recently, where both cytokines are hypothesized to counteract each other. According to this model, different autoimmune diseases can be viewed as disequilibrium between both cytokines. As this model may have important clinical implicat...

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Hlavní autoři: Cantaert, Tineke, Baeten, Dominique, Tak, Paul P, van Baarsen, Lisa GM
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991015/
https://ncbi.nlm.nih.gov/pubmed/21062511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3150
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