Attenuated Response of Aged Mice to Respiratory Francisella novicida Is Characterized by Reduced Cell Death and Absence of Subsequent Hypercytokinemia

BACKGROUND: Pneumonia and pulmonary infections are major causes of mortality among the growing elderly population. Age associated attenuations of various immune parameters, involved with both innate and adaptive responses are collectively known as immune senescence. These changes are likely to be in...

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Detalhes bibliográficos
Main Authors: Mares, Chris A., Sharma, Jyotika, Ojeda, Sandra S., Li, Qun, Campos, Jocelyn A., Morris, Elizabeth G., Coalson, Jacqueline J., Teale, Judy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990712/
https://ncbi.nlm.nih.gov/pubmed/21124895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014088
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