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Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway
Oxidized glutathione (GSSG) is commonly viewed as a byproduct of GSH metabolism. The pathophysiological significance of GSSG per se remains poorly understood. Adopting a microinjection approach to isolate GSSG elevation within the cell, this work identifies that GSSG can trigger neural HT4 cell deat...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990696/ https://ncbi.nlm.nih.gov/pubmed/19373248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.37 |
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