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Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea.

Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct-acting alkylating agent N-ethyl-N-nitrosourea (EtNU). We prepared DNA for transfection of NIH 3T3 cells from primary glial tumors of the brain and from schwannomas of the crani...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Perantoni, A O, Rice, J M, Reed, C D, Watatani, M, Wenk, M L
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3476947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.17.6317
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