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Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation

The primary cilium acts as a transducer of extracellular stimuli into intracellular signaling [1, 2]. Its regulation, particularly with respect to length, has been defined primarily by genetic experiments and human disease states in which molecular components that are necessary for its proper constr...

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Detalhes bibliográficos
Main Authors: Besschetnova, Tatiana Y., Kolpakova-Hart, Elona, Guan, Yinghua, Zhou, Jing, Olsen, Bjorn R., Shah, Jagesh V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990526/
https://ncbi.nlm.nih.gov/pubmed/20096584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.11.072
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