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Kinesin-2 Controls Development and Patterning of the Vertebrate Skeleton by Hedgehog- and Gli3-Dependent Mechanisms

Hedgehog signaling plays an essential role in patterning of the vertebrate skeleton. Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacia...

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Autors principals: Hart, Elona Kolpakova, Jinnin, Masatoshi, Hou, Bo, Fukai, Naomi, Olsen, Bjorn R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062520/
https://ncbi.nlm.nih.gov/pubmed/17698054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.07.018
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