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Kinesin-2 Controls Development and Patterning of the Vertebrate Skeleton by Hedgehog- and Gli3-Dependent Mechanisms

Hedgehog signaling plays an essential role in patterning of the vertebrate skeleton. Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacia...

詳細記述

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書誌詳細
主要な著者: Hart, Elona Kolpakova, Jinnin, Masatoshi, Hou, Bo, Fukai, Naomi, Olsen, Bjorn R.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062520/
https://ncbi.nlm.nih.gov/pubmed/17698054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.07.018
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