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Kinesin-2 Controls Development and Patterning of the Vertebrate Skeleton by Hedgehog- and Gli3-Dependent Mechanisms
Hedgehog signaling plays an essential role in patterning of the vertebrate skeleton. Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells results in severe patterning defects in the craniofacia...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2062520/ https://ncbi.nlm.nih.gov/pubmed/17698054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.07.018 |
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