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The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

Identification of the signaling pathways that control the proliferation of stem cells (SCs), and whether they act in a cell or non-cell autonomous manner, is key to our understanding of tissue homeostasis and cancer. In the adult Drosophila midgut, the Jun N-Terminal Kinase (JNK) pathway is activate...

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Hlavní autoři: Karpowicz, Phillip, Perez, Jessica, Perrimon, Norbert
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990205/
https://ncbi.nlm.nih.gov/pubmed/21098564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.060483
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