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Expression of enzymatically active poliovirus RNA-dependent RNA polymerase in Escherichia coli.

The poliovirus genome is replicated by a virus-encoded RNA-dependent RNA polymerase (RNA polymerase). The RNA polymerase is first synthesized as a larger precursor polypeptide, which is subsequently processed by a viral proteinase, 3Cpro, to give the mature polymerase molecule, 3Dpol. To further cha...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Morrow, C D, Warren, B, Lentz, M R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2819863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.17.6050
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