The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.
In vitro-transcribed human interferon-beta (IFN-beta) mRNA, which contains all the sequence of the natural molecule, is poorly translated in a reticulocyte lysate or when injected in Xenopus oocytes. This low level of translation is due to an inhibition by the 5' and 3' untranslated regions (UTRs)....
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1987
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3476924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.17.6030 |
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