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The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

In vitro-transcribed human interferon-beta (IFN-beta) mRNA, which contains all the sequence of the natural molecule, is poorly translated in a reticulocyte lysate or when injected in Xenopus oocytes. This low level of translation is due to an inhibition by the 5' and 3' untranslated regions (UTRs)....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kruys, V, Wathelet, M, Poupart, P, Contreras, R, Fiers, W, Content, J, Huez, G
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3476924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.17.6030
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