Ectopic T Cell Receptor-α Locus Control Region Activity in B Cells Is Suppressed by Direct Linkage to Two Flanking Genes at Once

The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα LCR DNA supports a gene expression pattern th...

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Main Authors: Knirr, Stefan, Gomos-Klein, Janette, Andino, Blanca E., Harrow, Faith, Erhard, Karl F., Kovalovsky, Damian, Sant'Angelo, Derek B., Ortiz, Benjamin D.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989920/
https://ncbi.nlm.nih.gov/pubmed/21124935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015527
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