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An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1
Mutations in superoxide dismutase 1 (SOD1) are associated with familial cases of amyotrophic lateral sclerosis (fALS). Studies in transgenic mice have suggested that wild-type (WT) SOD1 can modulate the toxicity of mutant SOD1. In the present study, we demonstrate that the effects of WT SOD1 on the...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989888/ https://ncbi.nlm.nih.gov/pubmed/20871097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq408 |
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