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Pyoderma Gangrenosum in a Patient with Bruton's X-linked Agammaglobulinemia: Shared Pathogenesis of Altered Tumor Necrosis Factor Alpha?

Individuals with Bruton's X-linked agammaglobulinemia (XLA) inherit a defect in the Btk gene, critical for B-cell differentiation. As a result, there is an absence of mature B-cells in the peripheral circulation with a marked reduction in serum levels of all immunoglobulin subtypes, predisposin...

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Autors principals: Schwartzfarb, Elissa M., Weir, Dot, Conlan, Walter A., Romanelli, Paolo, Kirsner, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: Matrix Medical Communications 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989809/
https://ncbi.nlm.nih.gov/pubmed/21103306
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