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Generation of Insulin-Producing Cells From Pluripotent Stem Cells: From the Selection of Cell Sources to the Optimization of Protocols
The pancreas arises from Pdx1-expressing progenitors in developing foregut endoderm in early embryo. Expression of Ngn3 and NeuroD1 commits the cells to form endocrine pancreas, and to differentiate into subsets of cells that constitute islets of Langerhans. β-cells in the islets transcribe gene-enc...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SBDR - Society for Biomedical Diabetes Research
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989781/ https://ncbi.nlm.nih.gov/pubmed/21060967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2010.7.82 |
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