Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression

Graft-versus-host disease (GVHD) causes significant morbidity and mortality in allogeneic hematopoietic stem cell transplantation (aHSCT), preventing its broader application to non–life-threatening diseases. We show that a single administration of a nondepleting monoclonal antibody specific for the...

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Detalhes bibliográficos
Main Authors: Albring, Jörn C., Sandau, Michelle M., Rapaport, Aaron S., Edelson, Brian T., Satpathy, Ansuman, Mashayekhi, Mona, Lathrop, Stephanie K., Hsieh, Chyi-Song, Stelljes, Matthias, Colonna, Marco, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989771/
https://ncbi.nlm.nih.gov/pubmed/21078889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102017
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