Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells.

Medullary thyroid carcinoma (MTC) is an endocrine tumor of the thyroid C cells that expresses high levels of the neuroendocrine peptide hormone calcitonin. During tumor progression in the host, there is an apparent loss of differentiation in MTC cells that involves a consistent decrease in calcitoni...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nakagawa, T, Mabry, M, de Bustros, A, Ihle, J N, Nelkin, B D, Baylin, S B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298975/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3112776/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.16.5923
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