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Extensive families of constant region genes in a phylogenetically primitive vertebrate indicate an additional level of immunoglobulin complexity.

A homologous probe for the constant region of the Heterodontus francisci (horned shark) immunoglobulin heavy chain was used to screen a genomic DNA library constructed in bacteriophage lambda, and a large number of independent clones were recovered. Their hybridization patterns with segment-specific...

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Detalhes bibliográficos
Main Authors: Kokubu, F, Hinds, K, Litman, R, Shamblott, M J, Litman, G W
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298964/
https://ncbi.nlm.nih.gov/pubmed/3475706
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