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Do PAKs make good drug targets?
p21-activated kinases (PAKs) act downstream of Rho-family GTPase and are linked to steps in both cancer initiation and progression. There are six mammalian PAK isoforms that are divided into two groups, and for different reasons both groups are attractive targets for cancer therapy. We describe the...
Kaydedildi:
| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Faculty of 1000 Ltd
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989626/ https://ncbi.nlm.nih.gov/pubmed/21173843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-70 |
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