Genome-wide Analysis of Genetic Loci Associated with Alzheimer’s Disease

CONTEXT: Genome wide association studies (GWAS) have recently identified CLU, PICALM and CR1 as novel genes for late-onset Alzheimer’s disease (AD). OBJECTIVE: In a three-stage analysis of new and previously published GWAS on over 35000 persons (8371 AD cases), we sought to identify and strengthen a...

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Main Authors: Seshadri, Sudha, Fitzpatrick, Annette L., Arfan Ikram, M, DeStefano, Anita L., Gudnason, Vilmundur, Boada, Merce, Bis, Joshua C., Smith, Albert V., Carassquillo, Minerva M., Charles Lambert, Jean, Harold, Denise, Schrijvers, Elisabeth M. C., Ramirez-Lorca, Reposo, Debette, Stephanie, Longstreth, W.T., Janssens, A. Cecile J.W., Shane Pankratz, V., Dartigues, Jean François, Hollingworth, Paul, Aspelund, Thor, Hernandez, Isabel, Beiser, Alexa, Kuller, Lewis H., Koudstaal, Peter J., Dickson, Dennis W., Tzourio, Christophe, Abraham, Richard, Antunez, Carmen, Du, Yangchun, Rotter, Jerome I., Aulchenko, Yurii S., Harris, Tamara B., Petersen, Ronald C., Berr, Claudine, Owen, Michael J., Lopez-Arrieta, Jesus, Varadarajan, Badri N., Becker, James T., Rivadeneira, Fernando, Nalls, Michael A., Graff-Radford, Neill R., Campion, Dominique, Auerbach, Sanford, Rice, Kenneth, Hofman, Albert, Jonsson, Palmi V., Schmidt, Helena, Lathrop, Mark, Mosley, Thomas H., Au, Rhoda, Psaty, Bruce M., Uitterlinden, Andre G., Farrer, Lindsay A., Lumley, Thomas, Ruiz, Agustin, Williams, Julie, Amouyel, Philippe, Younkin, Steve G., Wolf, Philip A., Launer, Lenore J., Lopez, Oscar L., van Duijn, Cornelia M., Breteler, Monique M. B.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989531/
https://ncbi.nlm.nih.gov/pubmed/20460622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.574
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