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ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells
Carbohydrate responsive element-binding protein (ChREBP) is a transcription factor whose expression and activity are increased in pancreatic β-cells maintained at elevated glucose concentrations. We show here that ChREBP inactivation in clonal pancreatic MIN6 β-cells results in an increase in Pdx-1...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Academic Press
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989445/ https://ncbi.nlm.nih.gov/pubmed/20934404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.010 |
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