INHALED GM-CSF FOR FIRST PULMONARY RECURRENCE OF OSTEOSARCOMA; EFFECTS ON DISEASE FREE SURVIVAL AND IMMUNOMODULATION: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

PURPOSE: Osteosarcoma most commonly recurs in lung. Based on preliminary data on antitumor effects of GM-CSF in animal models, and promising phase 1 trials, we embarked on a feasibility study of inhaled granulocyte-macrophage colony stimulating factor (GM-CSF) in patients with first isolated pulmona...

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Huvudupphovsmän: Arndt, Carola A. S., Koshkina, Nadya V., Inwards, Carrie Y., Hawkins, Douglas S., Krailo, Mark D., Villaluna, Doojduen, Anderson, Peter M., Goorin, Allen M., Blakely, Martin L., Bernstein, Mark, Bell, Sharon A., Ray, Kaylee, Grendahl, Darryl C., Marina, Neyssa, Kleinerman, Eugenie S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989183/
https://ncbi.nlm.nih.gov/pubmed/20576718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0662
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