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Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition
Protein O-phosphorylation often occurs reciprocally with O-GlcNAc modification and represents a regulatory principle for proteins. O-phosphorylation of serine by glycogen synthase kinase-3β on Snail1, a transcriptional repressor of E-cadherin and a key regulator of the epithelial–mesenchymal transit...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989108/ https://ncbi.nlm.nih.gov/pubmed/20959806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.254 |
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