Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

Protein O-phosphorylation often occurs reciprocally with O-GlcNAc modification and represents a regulatory principle for proteins. O-phosphorylation of serine by glycogen synthase kinase-3β on Snail1, a transcriptional repressor of E-cadherin and a key regulator of the epithelial–mesenchymal transit...

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Autors principals: Park, Sang Yoon, Kim, Hyun Sil, Kim, Nam Hee, Ji, Suena, Cha, So Young, Kang, Jeong Gu, Ota, Ichiro, Shimada, Keiji, Konishi, Noboru, Nam, Hyung Wook, Hong, Soon Won, Yang, Won Ho, Roth, Jürgen, Yook, Jong In, Cho, Jin Won
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989108/
https://ncbi.nlm.nih.gov/pubmed/20959806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.254
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