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Aminopeptidases do not directly degrade tau protein

BACKGROUND: Tau hyperphosphorylation and aggregation to form intracellular neurofibrillar tangles is prevalent in a number of tauopathies. Thus there is current interest in the mechanisms involved in Tau clearance. It was recently reported that Tau can be degraded by an aminopeptidase known as the p...

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Main Authors: Chow, K Martin, Guan, Hanjun, Hersh, Louis B
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988785/
https://ncbi.nlm.nih.gov/pubmed/21054848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-48
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