Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

BACKGROUND: A critical therapeutic challenge in epithelial ovarian carcinoma is the development of chemoresistance among tumor cells following exposure to first line chemotherapeutics. The molecular and genetic changes that drive the development of chemoresistance are unknown, and this lack of mecha...

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Bibliographic Details
Main Authors: Hooks, Shelley B, Callihan, Phillip, Altman, Molly K, Hurst, Jillian H, Ali, Mourad W, Murph, Mandi M
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988731/
https://ncbi.nlm.nih.gov/pubmed/21044322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-289
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