Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions.
The liver is an important target for potential gene therapy because of the critical role it plays in intermediary metabolism and synthesis of serum proteins. We report the use of retroviral vectors for transfer of recombinant genes into primary mouse hepatocytes. Hepatocytes were grown in a defined...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1987
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3474659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.15.5335 |
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